CheckupDYSBIOSIS Cx

Last update: March 21th, 2019.

What is CheckupDYSBIOSIS Cx

 
 
CheckupDYSBIOSIS Cx is an innovative stool test that allows to know the state of the intestinal microbiota and detect any possible disorder in its microbial balance ―dysbiosis― that may affect general health (due to its metabolic, protective and nutritional functions), as well as act on the diet to recover its balance.
 
CheckupDYSBIOSIS Cx is specially designed so that the stool sample can be taken in the privacy of your home and can be transported safely and hygienically to the laboratory for further analysis.
 
CheckupDYSBIOSIS Cx allows, based on the results obtained, to determine the concentration of each of the species that make up the intestinal microbiota (muconutritive, regulatory and proteolytic microbiota), to help prevent and treat possible health problems through suggestions for action on the diet or by ingesting certain probiotics, since a dysbiosis can cause that certain metabolic functions are not carried out or that an opportunistic pathogen proliferates in the absence of another bacterium that prevents it.
 
 
 

What is checked?

 
 
CheckupDYSBIOSIS analyzes, with a simple sample of feces, all bacterial genera present in the digestive microbiome of the individual by ultrasequencing 16S rRNA (16S ribosomal RNA). Later it compares it with the rest of healthy microbiomes sequenced to date through a comparative bioinformatic analysis.
 
Our intestinal microbiota contains 100 billion microorganisms, including at least 1,000 different species of bacteria that comprise more than 3 million genes (150 times more than in the human genome). In fact, the intestinal microbiota can weigh up to 2 kg and, only a third of our intestinal microbiota is common to most people, while the other two thirds are specific in each person (conforming this with the years and the contact with our environment).
 
 

Main features

 
 

Non-invasive

Based on a simple stool analysis.

Handy

Specially designed so that the stool sample can be taken in the privacy of your home.

Understandable

Easy to understand report with additional action suggestions.

 
 

How the report looks like?

 
 
Once the laboratory has analyzed the feces, a final report is generated with the results, comments and personalized suggestions according to the species that make up its intestinal microbiota (muconutritive, regulatory and proteolytic microbiota), which includes different types of action suggestions and/or treatment.
 
 


Uses and purposes

 
 


 

Know the status of your intestinal microbiota in an easy, practical, non-invasive, effective and economical way, to allow you to make the best decisions related to your own health.


 

Assist in the detection of any possible disorder in your microbial balance that may affect general health (each person has their own microbiome, it’s like a fingerprint).


 

Detect possible actions on diet, as well as help assess the intake of certain probiotics (nutritional supplements) and/or drugs, to regain their balance.


 

Use as a report that can be shared based on a stool test, as an unbeatable starting point in your visit with your doctor or nutritionist.

 

Bibliographic references

 

Scientific publications

  1. Allin, K. H., Nielsen, T., & Pedersen, O. (2014). MECHANISMS IN ENDOCRINOLOGY: Gut microbiota in patients with type 2 diabetes mellitus. European Journal of Endocrinology, 172(4), R167–R177. doi:10.1530/eje-14-0874
  2. Aydin, Ö., Nieuwdorp, M., & Gerdes, V. (2018). The Gut Microbiome as a Target for the Treatment of Type 2 Diabetes. Current Diabetes Reports, 18(8). doi:10.1007/s11892-018-1020-6
  3. Gérard C and Vidal H(2018) Impact of gut microbiota on host glycemic control. Front. Endocrinol.
  4. 10:29. doi:10.3389/fendo.2019.00029

  5. Goodman, B., & Gardner, H. (2018). The microbiome and cancer. The Journal of Pathology, 244(5), 667–676. doi:10.1002/path.5047
  6. Han, H., Li, Y., Fang, J., Liu, G., Yin, J., Li, T., & Yin, Y. (2018). Gut Microbiota and Type 1 Diabetes. International Journal of Molecular Sciences, 19(4), 995. doi:10.3390/ijms19040995
  7. Kho, Z. Y., & Lal, S. K. (2018). The Human Gut Microbiome – A Potential Controller of Wellness and Disease. Frontiers in Microbiology, 9. doi:10.3389/fmicb.2018.01835
  8. Meng, C., Bai, C., Brown, T. D., Hood, L. E., & Tian, Q. (2018). Human Gut Microbiota and Gastrointestinal Cancer. Genomics, Proteomics & Bioinformatics, 16(1), 33–49. doi:10.1016/j.gpb.2017.06.002
  9. Mikó, E., Kovács, T., Sebő, É., Tóth, J., Csonka, T., Ujlaki, G., … Bai, P. (2019). Microbiome—Microbial Metabolome—Cancer Cell Interactions in Breast Cancer—Familiar, but Unexplored. Cells, 8(4), 293. doi:10.3390/cells8040293
  10. Scotti, E., Boué, S., Sasso, G. L., Zanetti, F., Belcastro, V., Poussin, C., … Hoeng, J. (2017). Exploring the microbiome in health and disease. Toxicology Research and Application, 1, 239784731774188. doi:10.1177/2397847317741884
  11. Selber-Hnatiw, S., Rukundo, B., Ahmadi, M., Akoubi, H., Al-Bizri, H., Aliu, A. F., … Baird, A. (2017). Human Gut Microbiota: Toward an Ecology of Disease. Frontiers in Microbiology, 8. doi:10.3389/fmicb.2017.01265
  12. Sun, L., Ma, L., Ma, Y., Zhang, F., Zhao, C., & Nie, Y. (2018). Insights into the role of gut microbiota in obesity: pathogenesis, mechanisms, and therapeutic perspectives. Protein & Cell, 9(5), 397–403. doi:10.1007/s13238-018-0546-3
  13. Zheng, P., Li, Z., & Zhou, Z. (2018). Gut microbiome in type 1 diabetes: A comprehensive review. Diabetes/Metabolism Research and Reviews, e3043. doi:10.1002/dmrr.3043