Longevity Checkup

First-line assessment. The test incorporates a series of Scores that provide an immediate, panoramic view of overall health status. By processing metabolic, vascular and cellular data in an integrated way, they provide an initial summary framework to assess the body’s homeostasis, anticipate risks of multi-organ dysfunction, and estimate resilience, biological age and the potential for healthy longevity before exploring each specific function in detail. These Scores are:

• PhenoAge. An estimate of phenotypic age based on chronological age and nine blood biomarkers. Comparison with chronological age provides a reference for biological ageing estimated by the model and helps put the body’s metabolic and inflammatory profile into context.
• Oxidative Stress Score. An assessment of redox balance using the available laboratory parameters. It integrates factors associated with oxidative burden and the body’s protective reserve to guide assessment of the balance between stress factors and the defences considered by the model.
• Resilience Score. A summary metric of estimated physiological resilience, expressed as a percentage. In this checkup, it combines Oxidative Stress Score and Longevity Score: a lower combined burden of the factors assessed corresponds to a higher resilience score.
• Longevity Score. An integrated indicator of factors related to healthy ageing. It weighs markers of metabolic stress and inflammation alongside available protective factors to identify areas to review and track over time. It complements the phenotypic age estimated by PhenoAge without predicting how many years a person will live.

Haematological and inflammatory profile. Blood count, ESR, ferritin and high-sensitivity C-reactive protein help put findings related to red blood cells, immune cells, platelets and inflammation into context within the longevity study.

Lipids and glucose metabolism. The lipid profile, glucose, HbA1c and insulin provide information on cardiometabolic factors assessed alongside body measurements and lifestyle habits.

Liver profile and proteins. ALP, AST, ALT, GGT and LDH, together with albumin and total protein, provide context for the biochemical findings included in the study.

Kidney and metabolic assessment. Creatinine, cystatin C, urea, BUN, uric acid, and urinary albumin and creatinine extend the available information on kidney function and metabolism.